Evaluation of the ETV Success Score to Improve Decision Making on the Management of Hydrocephalus Secondary to Pediatric Posterior Fossa Tumors

ETV Success Score To Improve Decision Making

Authors

  • Atta ur Rehman Khan Department of Neurosurgery, Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
  • Sarwat Rasheed Department of Community Medicine, Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
  • Malik Fahad Department of Neurosurgery, Allama Iqbal Teaching Hospital, Dera Ghazi Khan, Pakistan

DOI:

https://doi.org/10.37978/tijfs.v7i1.416

Keywords:

hydrocephalus, posterior fossa tumors, endoscopic third ventriculostomy, neuroendoscopy

Abstract

Introduction: Children with posterior fossa tumors (PFT) often have hydrocephalus, which can be treated via endoscopic third ventriculostomy (ETV) before the tumor is removed, thereby improving surgical outcomes. Additionally, a scoring system that forecasts ETV success can help with this procedure's decision-making. The purpose of the research is to assess the effectiveness of electrotherapy (ETV) in treating PFT-related hydrocephalus and the predictive validity of the ETV effectiveness score.

Materials and Methods: A retrospective analysis was conducted on patients aged < 18 years who received ETV prior to PFT resection between 2022 and 2023. For every patient, the ETV success score was acquired retroactively, and its ability to forecast success contrasted with the actual success was noted.

Results: In the first six months after ETV, a worldwide success rate of 61.7% was observed in 40 surgical patients. For patients who were reviewed a year after surgery, this percentage decreased to 52.8%. The histological level of the tumor and the age of the victim did not correlate with the recovery rate. At both time periods, the ETV effectiveness score showed adequate accuracy (AUC = 0.671 at six months, AUC = 0.649 at one year).
Conclusion: In summary, ETV has been shown to be a safe treatment that may effectively cure hydrocephalus in individuals with PFT. In addition, the ETV efficacy score can be a valuable tool for predicting the likelihood of successful endoscopic surgery.

Downloads

Download data is not yet available.

References

Bognár L, Borgulya G, Benke P, Madarassy G. Analysis of CSF shunting procedure requirement in children with posterior fossa tumors. Childs Nerv Syst. 2003;19(5- 6):332-6.

Culley DJ, Berger MS, Shaw D, Geyer R. An analysis of factors determining the need for ventriculoperitoneal shunts after posterior fossa tumor surgery in children. Neurosurgery. 1994;34(3):402-7; discussion 7-8.

El-Gaidi MA, El-Nasr AH, Eissa EM. Infratentorial complications following preresection CSF diversion in children with posterior fossa tumors. J Neurosurg Pediatr. 2015;15(1):4-11.

Tamburrini G, Pettorini BL, Massimi L, Caldarelli M, Di Rocco C. Endoscopic third ventriculostomy: the best option in the treatment of persistent hydrocephalus after posterior cranial fossa tumour removal? Childs Nerv Syst. 2008;24(12):1405-12.

Schijman E, Peter JC, Rekate HL, Sgouros S, Wong TT. Management of hydrocephalus in posterior fossa tumors: how, what, when? Childs Nerv Syst. 2004;20(3):192-4.

Longatti P, Fiorindi A, Perin A, Martinuzzi A. Endoscopic anatomy of the cerebral aqueduct. Neurosurgery. 2007;61(3 Suppl):1-5; discussion -6.

Depreitere B, Dasi N, Rutka J, Dirks P, Drake J. Endoscopic biopsy for intraventricular tumors in children. J Neurosurg. 2007;106(5 Suppl):340-6.

Dewan MC, Lim J, Shannon CN, Wellons JC, 3rd. The durability of endoscopic third ventriculostomy and ventriculoperitoneal shunts in children with hydrocephalus following posterior fossa tumor resection: a systematic review and time-to-failure analysis. J Neurosurg Pediatr. 2017;19(5):578-84.

Dias MS, Albright AL. Management of hydrocephalus complicating childhood posterior fossa tumors. Pediatr Neurosci. 1989;15(6):283-9; discussion 90.

Lin CT, Riva-Cambrin JK. Management of posterior fossa tumors and hydrocephalus in children: a review. Childs Nerv Syst. 2015;31(10):1781-9.

Kumar V, Phipps K, Harkness W, Hayward RD. Ventriculo-peritoneal shunt requirement in children with posterior fossa tumours: an 11-year audit. Br J Neurosurg. 1996;10(5):467-70.

Azab W, Al-Sheikh T, Yahia A. Preoperative endoscopic third ventriculostomy in children with posterior fossa tumors: an institution experience. Turk Neurosurg. 2013;23(3):359-65.

Bhatia R, Tahir M, Chandler CL. The management of hydrocephalus in children with posterior fossa tumours: the role of pre-resectional endoscopic third ventriculostomy. Pediatr Neurosurg. 2009;45(3):186-91.

Beltagy MA, Kamal HM, Taha H, Awad M, El Khateeb N. Endoscopic third ventriculostomy before tumor surgery in children with posterior fossa tumors, CCHE experience. Childs Nerv Syst. 2010;26(12):1699-704.

Sainte-Rose C, Cinalli G, Roux FE, Maixner R, Chumas PD, Mansour M, et al. Management of hydrocephalus in pediatric patients with posterior fossa tumors: the role of endoscopic third ventriculostomy. J Neurosurg. 2001;95(5):791-7.

Ruggiero C, Cinalli G, Spennato P, Aliberti F, Cianciulli E, Trischitta V, et al. Endoscopic third ventriculostomy in the treatment of hydrocephalus in posterior fossa

Kulkarni AV, Drake JM, Mallucci CL, Sgouros S, Roth J, Constantini S, et al. Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus. J Pediatr. 2009;155(2):254-9.e1.

Furtado LMF, da Costa Val Filho JA, Dos Santos Júnior EC. External validation of the ETV success score in 313 pediatric patients: a Brazilian single-center study. Neurosurg Rev. 2021;44(5):2727-34.

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Bull World Health Organ. 2007;85(11):867-72.

Srinivasan HL, Foster MT, van Baarsen K, Hennigan D, Pettorini B, Mallucci C. Does pre-resection endoscopic third ventriculostomy prevent the need for post- resection CSF diversion after pediatric posterior fossa tumor excision? A historical cohort study and review of the literature. J Neurosurg Pediatr. 2020:1-10.

da Costa Val Filho JA, da Silva Gusmão SN, Furtado LMF, de Macedo Machado Filho G, Maciel FLA. The role of the Liliequist membrane in the third ventriculostomy. Neurosurg Rev. 2021;44(6):3375-85.

Tamburrini G, Frassanito P, Bianchi F, Massimi L, Di Rocco C, Caldarelli M. Closure of endoscopic third ventriculostomy after surgery for posterior cranial fossa tumor: the "snow globe effect". Br J Neurosurg. 2015;29(3):386-9.

Raimondi AJ, Tomita T. Hydrocephalus and infratentorial tumors. Incidence, clinical picture, and treatment. J Neurosurg. 1981;55(2):174-82.

Furtado LMF, da Costa Val Filho JA, Holliday JB, da Silva Costa J, de Matos MA, Nascimento VAM, et al. Endoscopic third ventriculostomy in patients with myelomeningocele after shunt failure. Childs Nerv Syst. 2020;36(12):3047-52.

Fiorillo A, Maggi G, Martone A, Migliorati R, D'Amore R, Alfieri E, et al. Shunt-related abdominal metastases in an infant with medulloblastoma: long-term remission by systemic chemotherapy and surgery. J Neurooncol. 2001;52(3):273-6.

Riva-Cambrin J, Detsky AS, Lamberti-Pasculli M, Sargent MA, Armstrong D, Moineddin R, et al. Predicting postresection hydrocephalus in pediatric patients with posterior fossa tumors. J NeurosurgPediatr. 2009;3(5):378-85.

El-Ghandour NM. Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in the treatment of obstructive hydrocephalus due to posterior fossa tumors in children. Childs Nerv Syst. 2011;27(1):117-26.

Downloads

Published

2024-03-13

How to Cite

Khan, A. ur R., Rasheed, S., & Fahad, M. (2024). Evaluation of the ETV Success Score to Improve Decision Making on the Management of Hydrocephalus Secondary to Pediatric Posterior Fossa Tumors: ETV Success Score To Improve Decision Making. The International Journal of Frontier Sciences, 7(1). https://doi.org/10.37978/tijfs.v7i1.416